SINGLE TRANSGENE

The following tabulates the mammary tumors in mice with a single transgene from the archives of the U.C.D. Department of Medical Pathology Transgenic Pathology Laboratory from 1990 through 1997.
The Genotypes are linked to the OMIM site for identification and narrative. The brackets are linked to bibliography. The Phenotype refers to the histological type and are linked to definitions and/or prototype images. These images can be compared on the Key page. The writtenglossary can be found by clicking here.
 PHENOTYPE
 
GENOTYPE Mice Tumors LC NOD SmC PAP ACa KA SqCa ScCa Dunn NOS Sarcoma Lym
CK II
3
3
0
0
0
1
1
1
0
0
0
0
0
0
(14) Cyclin D1
11
29
0
0
1
14
5
9
0
0
0
0
0
0
Epi-Phos
17
24
0
0
0
7
8
3
0
0
0
2
1
3
F9S
3
5
0
0
0
0
4
0
0
0
1
0
0
0
FGFr
4
4
0
0
0
3
1
0
0
0
0
0
0
0
formin KO
1
1
0
0
1
0
0
0
0
0
0
0
0
0
FRAP
9
14
0
0
5
2
4
2
0
0
1
0
0
2
Heregulin
19
34
0
0
0
4
9
14
1
0
6
0
0
0
HPV-E6/E7
1
    1
0
0
0
0
0
0
0
0
0
1
0
 0
(7) Int-2
42
77
0
0
0
23
21
14
0
0
17
1
1
0
IP-10
4
11
0
0
0
4
0
6
1
0
0
0
0
0
JNKAPF
2
4
0
0
0
3
0
0
0
0
0
1
0
0
KGF
23
93
0
0
0
0
78
9
0
1
2
0
0
0
MeKEE
2
10
0
0
1
1
0
6
0
0
2
0
0
0
(5)Myc
20
20
16
0
0
1
4
0
0
0
0
0
0
0
(19)Neu
59
279
9
253
0
3
6
3
4
0
0
0
1
0
Neu-NDL
25
33
0
25
2
4
0
2
0
0
0
0
0
0
Neu-un(8)
40
125
0
125
0
0
0
0
0
0
0
0
0
0
notch
2
5
0
0
0
0
3
0
0
0
0
2
0
0
p53
26
34
0
1
0
0
2
0
0
10
0
4
11
6
PyV-MT (c3)
1
2
0
1
0
1
0
0
0
0
0
0
0
 0
PyV-LTN(p1)
6
9
0
0
0
6
1
2
0
0
0
0
0
0
(6)PyV-MT WT
81
90
0
0
1
41
36
4
0
5
0
0
3
0
(26)PyV-MTx1MU
26
66
0
1
9
5
4
0
0
26
3
8
0
0
PyV-MT x2MU
20
42
0
12
0
2
20
4
2
2
0
0
0
0
RAR
4
5
0
0
0
2
0
0
0
0
0
0
0
3
(11)Ras
12
16
0
0
9
0
6
0
0
0
0
0
1
0
sag5
7
21
0
0
0
0
1
5
1
0
9
5
0
0
Shc3
1
2
0
0
0
2
0
0
0
0
0
0
0
0
(18)Src257
18
50
0
0
0
4
15
11
0
19
0
0
0
1
Stromelysin
36
39
0
0
0
1
6
0
0
0
0
1
0
31
(24)TGFa 
7
19
0
2
0
0
8
9
0
0
0
0
0
0
tpr-met(20)Met(TPR)
12
18
0
0
0
2
13
2
0
1
0
0
0
0
UK
1
5
0
0
0
0
4
0
0
0
0
0
1
0
waved-2Waved
2
2
0
0
0
0
0
0
0
0
0
2
0
0
wnt1(Int-1)
7
7
0
0
0
1
3
2
0
0
0
1
0
0
wnt10b
25
56
4
0
0
0
8
2
0
0
42
0
0
0
TOTALS=
579
1255
29
420
29
137
271
110
9
64
83
28
19
46
The following table is the summary of all single transgenic animals with mammary tumors in the archives of the U.C.D. Department of Pathology Transgenic Pathology Laboratory from 1990 through 1997. The images for the key can be found by clicking here or on individual tumors. 
Mice Tumors LC NOD SmC PAP ACa KA SqCa ScCa Dunn NOS Sarcoma Lym
TOTAL=
579
1255
29
420
29
137
271
110
9
64
83
28
19
46
 
TRANGENES WITH TUMORS= 36
MAMMARY TUMORS= 1150
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Image Key
 
Last Update: 7/21/98
Name: Medical Pathology
Email: rdcardiff@ucdavis.edu