The Receptor Kinase Receptor Pathway

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The receptor tyrosine kinase pathway in breast cancer is dominated by the erbB family. ErbB2/Her2/neu is found over expressed in about 1/3 of human breast cancers. This pathway has been extensively modeled in GEM. Find the gene of interest. If it is a hot-link, it will show a cursor hand. Click on the Hot-Spot to see the information about the gene.