Transgenic Mammary Tumors




ONE TRANSGENE (1990-95)

*E.C. MATRIX*
Examples linked to Images and Text=>>	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
Stromelysin	4	5	0	0	0	0	4	0	1
subtotal	4	5	0	0	0	0	4	0	1

*GROWTH FACTORS*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
FGFb4(Int-2)	34	44	0	2	2	11	7	9	13
Heregulin(IJ)	16	23	0	0	0	1	10	11	1
Heregulin(IK)	1	1	0	0	0	1	0	0	0
IP-10	4	6	0	0	1	1	1	1	1
KGF	12	24	0	0	0	0	8	9	7
TGFa	11	18	0	2	0	2	14	0	0
Wnt-1(Int-1)	7	7	0	0	0	1	3	2	1
Wnt-10	3	5	0	0	0	0	4	0	1
subtotal	88	128	0	4	3	17	47	32	24

*MEMB. RECEPTORS*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
FGFr	10	11	0	0	0	5	3	1	2
FGFr:AP	3	6	0	0	0	0	4	0	2
Neu	45	81	0	65	0	4	8	4	0
Neu(ECD)	7	21	0	21	0	0	0	0	0
Neu/Un	22	32	0	17	11	2	1	0	1
Met	12	15	0	0	0	1	12	2	0
subtotal	99	166	0	103	11	12	28	7	5

*SIGNAL TRANSDUCTION*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
PyV-MT	86	91	0	3	1	32	47	3	5
PyV-MT 1xMUT	9	10	0	0	0	2	3	0	5
PyV-MT 2xMUT	19	32	0	12	0	0	14	6	0
PyV-MT(c3)	1	2	0	1	0	1	0	0	0
Ras	1	1	0	0	0	0	0	0	1
Src 257	17	23	0	0	3	2	6	3	9
subtotal	133	159	0	16	4	37	70	12	20

*CELL CYCLE*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
Cyclin D-1	9	9	0	0	0	1	2	6	0
HPV E6/E7	1	1	0	0	0	0	0	0	1
PyV-LTN	4	4	0	0	0	2	0	2	0
subtotal	14	14	0	0	0	3	2	8	1

*NUCLEAR TRANSCRIPTION*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
Casein Kinase II	1	1	0	0	0	1	0	0	0
Myc	31	33	27	0	0	1	4	0	1
Epsilon Pase	1	1	0	0	0	0	0	0	1
subtotal	33	35	27	0	0	2	4	0	2

*UNKNOWN*
	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
orf7	2	1	0	0	0	0	1	0	1
SAG(MTV-7)	3	3	0	0	0	0	1	1	1
subtotal	5	4	0	0	0	0	2	1	2

	NO.	NO.TU	LC	NOD	SmC	PAP	ACa	KA	NOS
TOTALS=	376	511	27	123	18	71	157	60	55

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