TABLE 5 PHENOTYPIC MARKERS

Transgene Expression IHC or ISH
Nuclear receptors ER, PR
Myoepithelium Smooth Muscle Actin
Luminal Cell Cytokeratin, Muc-1, casein, lactalbumin, lactogloblin
Basement Membrane Laminin, collagen IV, PAS,
Proliferation (S-phase)/Apoptosis Ki67/Tunel assays
Other Vascular markers (CD31[PECAM],( SMA), neuroendocrine , p53