The Pathology of Transgenic Mice

Robert D. Cardiff, M.D., Ph.D.
Professor of Pathology and Medical Informatics
Department of Pathology
School of Medicine
University of California, Davis

Neoplastic progression in PyV-MT transgenic tumors.

Almost 80% of all mouse mammary tumors metastasize. Some transgenic lines have a very high rate of metastasis. The animals with the Polyoma Virus Middle T transgene form tumors and have pulmonary metastases within 6 weeks of birth.

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LAST ENTERED March 31, 1997