BENIGN BREAST PATHOLOGY:

SCLEROSING ADENOSIS

This entity usually is seen in association with fibrocystic change. It is a descriptive diagnosis. Sclerosing means too much stroma. Adenosis means too much glandular tissue.

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Slide 73. A duct (D) is noted in this subgross slice. Several smaller ducts end with tangles of elongated ductules. One focus is delineated. This is SCLEROSING ADENOSIS. Photographed at 6.3x magnification.
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Slide 74. This subgross slice shows a cellular focus of sclerosing adenosis. Note the rounded border, a hallmark of a benign condition. Photographed at 3.2x magnification.
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Slide 75 The histologic appearance of three foci of sclerosing adenosis. Each is centered around a terminal duct. To the examining fingers, such foci may feel as tiny "buck shots". Photographed at 10x.
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Slide 76. Note the distinct round border of sclerosing adenosis. Photographed at 10x magnification.

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Slide 77. The histologic pattern depicts crowded ductules. The arrow points to a myoepithelial cell of one ductule surrounded by a thickened basement membrane. Photographed at 25x magnification.
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Slide 78. Dense stroma is "pulling" the ductules into odd shapes. Photographed at 63x magnification.
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Slide 79. At higher magnification, the arrow points to a myoepithelial cell. Photographed at 250x magnification.

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slide73.jpg 435.50 Kb Slide 73. A duct (D) is noted in this subgross slice. Several smaller ducts end with tangles of elongated ductules. One focus is delineated. This is SCLEROSING ADENOSIS. Photographed at 6.3x magnification.	slide74.jpg 403.38 Kb Slide 74. This subgross slice shows a cellular focus of sclerosing adenosis. Note the rounded border, a hallmark of a benign condition. Photographed at 3.2x magnification.	slide75.jpg 991.79 Kb Slide 75 The histologic appearance of three foci of sclerosing adenosis. Each is centered around a terminal duct. To the examining fingers, such foci may feel as tiny "buck shots". Photographed at 10x.	slide76.jpg 942.35 Kb Slide 76. Note the distinct round border of sclerosing adenosis. Photographed at 10x magnification.
slide77.jpg 837.27 Kb Slide 77. The histologic pattern depicts crowded ductules. The arrow points to a myoepithelial cell of one ductule surrounded by a thickened basement membrane. Photographed at 25x magnification.	slide78.jpg 612.37 Kb Slide 78. Dense stroma is "pulling" the ductules into odd shapes. Photographed at 63x magnification.	slide79.jpg 342.83 Kb Slide 79. At higher magnification, the arrow points to a myoepithelial cell. Photographed at 250x magnification.