BENIGN BREAST CONDITIONS:

FIBROCYSTIC CHANGE (APOCRINE CYSTS)

The human breast has many types of benign epithelial lesions. These are examples of benign cysts of the breast.. The apocrine cysts illustrated here are another source of cysts that account for "lumpy" breasts. The tall columnar cells with pink cytoplasm resemble the apocrine sweat glands in the axilla, leading to the term "apocrine".

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Slide 67. The slice shows a partially unfolded lobule with the arrow pointing to the terminal duct. Note the punctate appearance of the epithelium. Photographed at 6.3x magnification. 
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Slide 68. In the corresponding histologic slide, the arrow points to the terminal duct. Photographed at 6.3x magnification.

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Slide 69. The histologic slide displays tufts of cells with intensely pink cytoplasm, the arrow points to one. Since these epithelial cells look like cells of apocrine sweat glands in the axilla, these cysts were called APOCRINE CYSTS. Photographed at 25x magnification. 

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Slide 70. The arrow points to one cellular tuft in this subgross slice showing an apocrine cyst. Note the speckels lining the cyst wall. Photographed at 6.3x magnification. 
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Slide 71. Part of the cyst is lined by apocrine cells the other with plain epithelium in this slice. Photographed at 6.3x magnification. 
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Slide 72. The epithelium of an apocrine cyst shows prominent apical "snouts" that slough off into the lumen. Photographed at 100x magnification. 

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