BENIGN BREAST CONDITIONS:

FIBROCYSTIC CHANGE (EPITHELIAL CYSTS)

The human breast has many types of benign epithelial lesions. These are examples of benign cysts of the breast.. The simple epithelial cysts illustrated here, in part, account for "lumpy" breasts.

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Slide 59. A gross specimen shows two "blue domed cysts separated by dense connective tissue. The term "blue dome" is applied to these cysts that are filled with blood. Thus, they stick out of the surrounding connective tissue as dark blue domes. 
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Slide 60. This diagram depicts the development of cysts. On the left the subgross and on the right the histologic appearances are seen. 
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Slide 61. In this slice a totally unfolded lobule has been converted into a cyst. The arrow points to its terminal duct that is attached to the duct tree. Photographed at 6.3x magnification. 
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Slide 62. The histologic preparation shows early cystic change of one lobule. Photographed at 10x magnification. 
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Slide 63. At higher magnification the arrows point to broken walls of distended ductules. It is lined by normal epithelium, so it is called an EPITHELIAL CYST. Photographed at 25x magnification 
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Slide 64. Multiple broken walls are noted in this lobule converting into an epithelial cyst. Photographed at 25x magnification. 
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Slide 65. In this slice the arrow points to the terminal duct of a fully unfolded epithelial cyst filled with secretion. The other cyst is partially unfolded. Photographed at 6.3x magnification. 
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Slide 66. Two cysts are hanging from the duct tree in this slice. Many cysts can combine to form a clinically palpable cyst in a woman's breast. Photographed at 4x magnification.