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Slide 98. A 5 mm in diameter focus of ductal carcinoma in-situ is seen in this slice. The distal end of the terminal duct is distended by cells. The proximal terminal duct is labeled T.D. Below the terminal duct a cluster of coarse ductules is noted. A general rule is: Ductal hyperplasia is usually < 3mm in greatest diameter. DUCTAL CARCINOMA IN-SITU (DCIS) is >3 mm in diameter. Photographed at 6.3x magnification
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Slide 99. The corresponding histologic slide shows the distended distal part of the terminal duct. An arrow points to the proximal part of the terminal duct. The double arrow points to the area magnified. Photographed at 10x magnification
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Slide 100. The cell population is monotonous as if it is a single clonal derivative (cytologic criterion). The spaces are regular, of small size with rigid cell bars and protrusions (histologic criteria). This is ductal carcinoma in-situ (DCIS) CRIBRIFORM PATTERN. Photographed at 63x magnification
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Slide 101. Note the monotony of the cell population. Photographed at 250x magnification