"DUCTAL" HYPERPLASIA:

Atypical Hyperplasia

This is the most extreme case of ductal hyperplasia.

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slide94.jpg
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Slide 94. The subgross image shows a cellular focus of coarse ductules below the ducts. Photographed at 6.3x magnification
slide95.jpg
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Slide 95. The corresponding histologic slide shows the large cellular ductules. Photographed at 6.3x magnification

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Slide 96. At higher magnification most of the spaces within the ductules are small and round. Photographed at 25x magnification
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Slide 97. At higher magnification the more regular round spaces are seen to be surrounded by cells that still show some pleomorphism. This is DUCTAL HYPERPLASIA WITH ATYPIA (DHA). Not all criteria for carcinoma in-situ are present so it is a "borderline" lesion. Photographed at 63x magnification

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slide94.jpg 332.77 Kb Slide 94. The subgross image shows a cellular focus of coarse ductules below the ducts. Photographed at 6.3x magnification	slide95.jpg 753.16 Kb Slide 95. The corresponding histologic slide shows the large cellular ductules. Photographed at 6.3x magnification
slide96.jpg 623.17 Kb Slide 96. At higher magnification most of the spaces within the ductules are small and round. Photographed at 25x magnification	slide97.jpg 505.20 Kb Slide 97. At higher magnification the more regular round spaces are seen to be surrounded by cells that still show some pleomorphism. This is DUCTAL HYPERPLASIA WITH ATYPIA (DHA). Not all criteria for carcinoma in-situ are present so it is a "borderline" lesion. Photographed at 63x magnification