"DUCTAL" HYPERPLASIA:

Florid Hyperplasia

This is the most extreme case of typical hyperplasia.

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Slide 90. In this slice a duct (D) is noted. Multiple coarse lobules are studding the duct. When the duct tree shows many foci close together of ductal hyperplasias there seems to be a "field effect" for these lesions to become cancerous. Photographed at 6.3x magnification 
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Slide 91. A single focus of 5-8 coarse ductules appears in this image. One ductule is outlined by 3 arrows. Photographed at 6.3x magnification 
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Slide 92. In the corresponding histologic slide an arrow points to the coarse ductule outlined in the slice. Photographed at 25x magnification 
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Slide 93 At higher magnification, irregular spaces are seen surrounded by pleomorphic "streaming" of the cells. This is DUCTAL HYPERPLASIA, FLORID (DHF). It is considered a benign hyperplasia even though it has a necrotic center. Photographed at 63x magnification 

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