BETTER PROGNOSIS INVASIVE BREAST CANCERS.

These kinds of cancers constitute less than 14% of all breast cancers. They also represent distinctive morphological sub-types. Each have a better prognosis than the usual breast cancer NOS.

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Slide 168. These variants have better prognosis. 
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Slide 169. TUBULAR invasive breast cancer constitutes <5% of breast cancers. They tend to be small (<1 cm in diameter). They rarely metastasize to lymphnodes. Invariably they are positive for estrogen and progesterone receptors. Photographed at 25x magnification 
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Slide 170. A single cell layer forms the tubules. The arrow points to a "tear drop" Photographed at 63x magnification 
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Slide 171. The arrow points to a rigid bar crossing a tubule in this invasive tubular carcinoma. Photographed at 63x magnification 
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Slide 172. Balls of cancer cells are floating in gelatinous secretions. An example of COLLOID CARCINOMA. Photographed at 63x magnification 
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Slide 173. At higher magnification the cancer cells show moderate pleomorphism. Photographed at 63x magnification. 
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Slide 174. This invasive breast cancer is called LOBULAR because it is seen in association with lobular carcinoma in-situ. The arrow points to an INDIAN FILE (row of single cells). Photographed at 63x magnification 
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Slide 175. Medullary breast carcinoma is soft like the medulla or brain since it contains no hard collagen. ~20% of the tumor is lymphocytes surrounding the nests of cancer cells. Photographed at 25x magnification 
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Slide 176. At higher magnification the clusters of cancer cells are noted. In spite of the anaplastic features of the cancer the tumor does not infiltrate very often but grows in an expansile fashion. Photographed at 63x magnification 
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Slide 177. This is an example of PAPILLARY breast carcinoma. Photographed at 63x magnification 

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