INVASIVE BREAST CANCER WITH METASTASIS

Human breast cancer tends to spread locally through the lymphatics and to the lymph nodes. Distant metastases occur in many organs including the bone and liver.

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Slide 161. This invasive ductal carcinoma is moderately well differentiated. However, it has invaded a lymphatic vessel (arrow). Evidently the nerve (N) secretes cytokines tropic to the cancer. Photographed at 63x magnification
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Slide 162. The arrow points to another focus of lymphatic spread. Photographed at 25x magnification
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Slide 163. The arrow points to the capsule of a lymphnode in the axilla. An afferent lymphatic vessel (L) is stuffed with cancer cells. Photographed at 10x magnification
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Slide 164. This axillary lymphnode is almost replaced by a metastatic focus of breast carcinoma of the cribriform variant. Photographed at 10x magnification

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Slide 165. The artery (A) in this breast contains a tumor embolus of breast cancer. That is an indication of systemic metastatic disease. Photographed at 25x magnification
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Slide 166. The vertebrae were sliced at autopsy of a breast cancer patient. The gray-white areas represent metastases.
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Slide 167. The liver of this breast cancer patient shows numerous foci of metastases.

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slide161.jpg 645.33 Kb Slide 161. This invasive ductal carcinoma is moderately well differentiated. However, it has invaded a lymphatic vessel (arrow). Evidently the nerve (N) secretes cytokines tropic to the cancer. Photographed at 63x magnification	slide162.jpg 836.86 Kb Slide 162. The arrow points to another focus of lymphatic spread. Photographed at 25x magnification	slide163.jpg 1085.02 Kb Slide 163. The arrow points to the capsule of a lymphnode in the axilla. An afferent lymphatic vessel (L) is stuffed with cancer cells. Photographed at 10x magnification	slide164.jpg 2.40 Mb Slide 164. This axillary lymphnode is almost replaced by a metastatic focus of breast carcinoma of the cribriform variant. Photographed at 10x magnification
slide165.jpg 1079.38 Kb Slide 165. The artery (A) in this breast contains a tumor embolus of breast cancer. That is an indication of systemic metastatic disease. Photographed at 25x magnification	slide166.jpg 393.11 Kb Slide 166. The vertebrae were sliced at autopsy of a breast cancer patient. The gray-white areas represent metastases.	slide167.jpg 470.57 Kb Slide 167. The liver of this breast cancer patient shows numerous foci of metastases.