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Slide 122. In this slide a distended duct is seen in the center. The "misty" or "foggy" appearance in area labeled 1 is a focus of lobular carcinoma in-situ. The area labeled 2 is a focus of ductal hyperplasia. Photographed at 1.6x
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Slide 123. The corresponding histologic slide is seen labeled 1 and 2. 1 is a focus of lobular carcinoma in-situ. 2 is a focus of blunt duct adenonosis. Two different TDLU gave rise to these 2 lesions. Both processes are not seen within the same TDLU indicating that they have different pathogenic pathways. Photographed at 6.3x magnification
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Slide 124. The lobular carcinoma in-situ shows many ductules distended to > 4 times the usual diameter a characteristic of these lesions. Note the cell monotony. Photographed at 63x magnification
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Slide 125. The upper part of this subgross image depicts a focus of lobular carcinoma in-situ the lower left an area of normal lobules. Photographed at 6.3x magnification
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Slide 126. The corresponding histology contrasts the solid ductules of lobular carcinoma in-situ with normal ductules with open lumens. Photographed at 6.3x magnification
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Slide 127. The arrow points to the focus of lobular carcinoma in-situ magnified. Photographed at 6.3x magnification
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Slide 128. At higher magnification the distended ductules are filled with monotonous cells loosely adherent to each other. Photographed at 63x magnification
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Slide 129. The histologic slide shows a focus of lobular carcinoma in-situ. Photographed at 6.3x magnification
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Slide 130. At higher magnification some of the distended ductules show round spaces. Photographed at 25x magnification
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Slide 131. The cribriform pattern in the ductule at the top is a variant pattern of lobular carcinoma in-situ. Photographed at 63x magnification