ATYPICAL LOBULAR HYPERPLASIA:

This lesion is "lobular". These images show the usual pattern.

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Slide 116. A prominent terminal duct (TD) gives rise to a large lobule in this subgross. Photographed at 6.3x magnification 
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Slide 117. The corresponding histologic slide shows the terminal duct TD and surrounding lobular elements to be cellular. Photographed at 6.3x magnification 
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Slide 118. At higher magnification the cells are seen to be loosely adherent to each other, a key feature of ATYPICAL LOBULAR HYPERPLASIA and LOBULAR CARCINOMA IN-SITU. (Lobular lesions lack E-cadherin.) Photographed at 63x magnification 
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Slide 119. This histologic slide shows solidification but no distention of terminal duct and ductules. It is therefore atypical lobular hyperplasia and not lobular carcinoma in-situ. Photographed at 25x magnification 
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Slide 120. At higher magnification the monotomy of the cell population is appreciated. Photographed at 63x magnification 
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Slide 121. Another view of atypical lobular hyperplasia. Photographed at 63x magnification 

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