"DUCTAL" HYPERPLASIA:

Mild to Moderate Hyperplasia

This entity appears in the histologic preparation as a cluster of bigger structures, so pathologists called it ductal. However, the microarchitecture showed it to be an abnormal terminal duct lobular unit. The conventional pathologic names of these have been retained here.

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slide83.jpg
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Slide 83. This slide begins a series on increasingly severe ductal hyperplasia. The images on this page are considered mild to moderate "ductal" hyperplaisa. The arrow points to a branching terminal duct draining two cellular lobules composed of coarse ductules. Photographed at 6.3x magnification
slide84.jpg
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Slide 84. The corresponding histologic slide shows multi cellular lining of the ductules. The arrow points to cells bridging the lumen. This represents DUCTAL HYPERPLASIA, MILD (DHM). Photographed at 25x magnification

slide85.jpg
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Slide 85. A duct (D) is noted in this subgross image. The terminal duct is hidden behind the cluster of coarser ductules filled with cells. Photographed at 8x magnification
slide86.jpg
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Slide 86. The corresponding histologic slide shows the duct (D). Arrows point to the interphase between the lobule and extralobular stroma. Photographed at 10x magnification

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Slide 87. The cellular ductules are approaching the size of the duct, hence the term ductal. Note the loose intralobular stroma. Photographed at 25x magnification
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Slide 88. Note the differences in sizes and shapes (pleomorphism) of the cell population. A dual cell population in the cellular ductules is a hallmark of benign ductal hyperplasia. Photographed at 63x magnification

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Slide 89. Some ductules are displaying irregular spaces due to the irregular ingrowth of cells, another hallmark of benign ductal hyperplasia. An example of DUCTAL HYPERPLASIA, MODERATE. Photographed at 63x magnification

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slide83.jpg 501.10 Kb Slide 83. This slide begins a series on increasingly severe ductal hyperplasia. The images on this page are considered mild to moderate "ductal" hyperplaisa. The arrow points to a branching terminal duct draining two cellular lobules composed of coarse ductules. Photographed at 6.3x magnification	slide84.jpg 852.82 Kb Slide 84. The corresponding histologic slide shows multi cellular lining of the ductules. The arrow points to cells bridging the lumen. This represents DUCTAL HYPERPLASIA, MILD (DHM). Photographed at 25x magnification
slide85.jpg 423.36 Kb Slide 85. A duct (D) is noted in this subgross image. The terminal duct is hidden behind the cluster of coarser ductules filled with cells. Photographed at 8x magnification	slide86.jpg 871.68 Kb Slide 86. The corresponding histologic slide shows the duct (D). Arrows point to the interphase between the lobule and extralobular stroma. Photographed at 10x magnification
slide87.jpg 657.96 Kb Slide 87. The cellular ductules are approaching the size of the duct, hence the term ductal. Note the loose intralobular stroma. Photographed at 25x magnification	slide88.jpg 574.62 Kb Slide 88. Note the differences in sizes and shapes (pleomorphism) of the cell population. A dual cell population in the cellular ductules is a hallmark of benign ductal hyperplasia. Photographed at 63x magnification
slide89.jpg 585.42 Kb Slide 89. Some ductules are displaying irregular spaces due to the irregular ingrowth of cells, another hallmark of benign ductal hyperplasia. An example of DUCTAL HYPERPLASIA, MODERATE. Photographed at 63x magnification