8. Guy, CT; Webster, MA; Schaller, M; Parsons, TJ; Cardiff, RD; Muller, WJ. Expression of the neu protooncogene neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proceedings of the National Academy of Sciences of the United States of America, 1992 Nov 15, 89(22):10578-82. (ABSTRACT)(ILLUSTRATIONS)(UI: 93066287);

LEGEND:
(B) Photomicrograph of a hematoxylin/eosin-stained slide illustrating the expansile focus of solid tumor arising in the midst of a hyperplastic, dysplastic mammary gland (N#128, 210 days of age). Note that the dysplastic mammary cells lining dilated luminal spaces do not show lipid production. (x48). (C) Photomicrograph of a hematoxylin/eosin-stained slide demonstrating a typical nest of mammary adenocarcinoma cells metastatic in the lung (N#202, 221 days of age). Note that the metastasis is in solid nests which resemble those found in the primary tumors such as those illustrated in B. (x48).

LEGEND:
(B) Photomicrograph of a hematoxylin/eosin-stained slide illustrating the expansile focus of solid tumor arising in the midst of a hyperplastic, dysplastic mammary gland (N#128, 210 days of age). Note that the dysplastic mammary cells lining dilated luminal spaces do not show lipid production. (x48). (C) Photomicrograph of a hematoxylin/eosin-stained slide demonstrating a typical nest of mammary adenocarcinoma cells metastatic in the lung (N#202, 221 days of age). Note that the metastasis is in solid nests which resemble those found in the primary tumors such as those illustrated in B. (x48).
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