15. Cardiff, RD; Munn, RJ. Comparative pathology of mammary tumorigenesis in transgenic mice. Cancer Letters, 1995 Mar 23, 90(1):13-9. (ABSTRACT)(ILLUSTRATIONS)(UI: 95236410);

LEGEND:
Figure 1 A: High-magnification photomicrograph of eosinophilic, small cell tumor that is frequently associated with the ras oncogene. Note the round-to-oval small nuclei and pale cytoplasm. The cells are oriented perpendicular around the blood vessels. B: A basophilic, large cell tumor that is frequently associated with the myc oncogene photographed at the same magnification as (A) and (C). Note the pleomorphic nuclei with open chromatin patterns and prominent nuclei. The cells have dark-staining cytoplasm and are organized as psuedoacini. C: High-magnification photomicrograph that shows the pale-staining nodular intermediate cell tumor that is associated with the neu oncogene. Note the more uniform nuclei than the SC tumor and the a more open chromatin pattern than the LC tumor. The cells have a pale pink-staining cytoplasm and are organized as nodules. The bar in the lower-right corner indicates 10 microns.
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Last Updated: November 06, 1996